Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MED13L All Species: 18.18
Human Site: Y1420 Identified Species: 33.33
UniProt: Q71F56 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q71F56 NP_056150.1 2210 242602 Y1420 G G H R D V A Y I V V C P E N
Chimpanzee Pan troglodytes XP_001138050 2188 240763 L1396 C P E N E A L L N G A K S F F
Rhesus Macaque Macaca mulatta XP_001112106 2210 242628 Y1420 G G H R D V A Y I V V C P E N
Dog Lupus familis XP_534693 2280 250152 Y1489 G G H R D V A Y I V V C P E N
Cat Felis silvestris
Mouse Mus musculus Q6JPI3 2207 241740 Y1419 G G H R D V A Y I V V C P E N
Rat Rattus norvegicus NP_001101807 1374 149708 C619 L S A V Y E M C R L G Q H K P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509907 2170 238695 A1379 V L C P E N E A L L N G A K S
Chicken Gallus gallus XP_415317 2195 241321 Y1399 G G H R D V A Y I V V C P E N
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A2VCZ5 2102 230974 E1331 P F A L P Y W E K L L L D P Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7KTX8 2618 280005 G1825 S S Y N T V S G P L T W R Q F
Honey Bee Apis mellifera XP_393643 1982 216109 P1227 L L E P Y A G P R D V A Y V V
Nematode Worm Caenorhab. elegans Q93442 2862 325119 K1899 T L T R T Y E K M R L G R H I
Sea Urchin Strong. purpuratus XP_001203054 1127 123639 V372 P Y S S A R D V A Y I A L V P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 53.7 99.2 93.3 N.A. 92.4 57.7 N.A. 53.5 86.4 N.A. 50.2 N.A. 24.8 33.9 21.2 25.6
Protein Similarity: 100 69.3 99.6 94.7 N.A. 95.7 59.9 N.A. 69.7 92.5 N.A. 66.4 N.A. 41.5 50.5 38.5 35.1
P-Site Identity: 100 0 100 100 N.A. 100 0 N.A. 0 100 N.A. 0 N.A. 6.6 6.6 6.6 0
P-Site Similarity: 100 6.6 100 100 N.A. 100 13.3 N.A. 33.3 100 N.A. 13.3 N.A. 33.3 6.6 20 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 16 0 8 16 39 8 8 0 8 16 8 0 0 % A
% Cys: 8 0 8 0 0 0 0 8 0 0 0 39 0 0 0 % C
% Asp: 0 0 0 0 39 0 8 0 0 8 0 0 8 0 0 % D
% Glu: 0 0 16 0 16 8 16 8 0 0 0 0 0 39 0 % E
% Phe: 0 8 0 0 0 0 0 0 0 0 0 0 0 8 16 % F
% Gly: 39 39 0 0 0 0 8 8 0 8 8 16 0 0 0 % G
% His: 0 0 39 0 0 0 0 0 0 0 0 0 8 8 0 % H
% Ile: 0 0 0 0 0 0 0 0 39 0 8 0 0 0 8 % I
% Lys: 0 0 0 0 0 0 0 8 8 0 0 8 0 16 0 % K
% Leu: 16 24 0 8 0 0 8 8 8 31 16 8 8 0 0 % L
% Met: 0 0 0 0 0 0 8 0 8 0 0 0 0 0 0 % M
% Asn: 0 0 0 16 0 8 0 0 8 0 8 0 0 0 39 % N
% Pro: 16 8 0 16 8 0 0 8 8 0 0 0 39 8 16 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 8 0 8 0 % Q
% Arg: 0 0 0 47 0 8 0 0 16 8 0 0 16 0 0 % R
% Ser: 8 16 8 8 0 0 8 0 0 0 0 0 8 0 8 % S
% Thr: 8 0 8 0 16 0 0 0 0 0 8 0 0 0 0 % T
% Val: 8 0 0 8 0 47 0 8 0 39 47 0 0 16 8 % V
% Trp: 0 0 0 0 0 0 8 0 0 0 0 8 0 0 0 % W
% Tyr: 0 8 8 0 16 16 0 39 0 8 0 0 8 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _